Understanding Post-Surgical Fatigue Post-Surgical Fatigue Explained Experiencing fatigue after surgery is a common part of the body’s recovery process. Several factors contribute to this feeling of weakness, including: Surgical Trauma and Stress Response The body undergoes significant stress when it undergoes surgery, as the tissues are damaged and the body reacts by expending a lot of energy to repair the damage. This priority repair task can lead to a sense of overall weakness. Residual Effects of Anesthesia When anesthesia drugs are not fully metabolized, they can suppress neuromuscular function, resulting in feelings of limb weakness and mental lethargy. Nutritional and... Learn more