Breast hypoplasia denotes under-development of glandular parenchyma beyond two standard deviations from age-specific norms. The condition may be unilateral or bilateral, isolated or associated with systemic syndromes. Recognition is based on quantitative and qualitative deviations from expected breast morphology rather than on isolated patient perception. Deficient breast volumeA mammary projection that remains ≤ Tanner stage II after age 16 years, or a breast circumference difference ≥ 150 mL compared with the contralateral side, defines objective hypoplasia. AsymmetryUnilateral hypoplasia produces visible volume discrepancy, often accompanied by contralateral hypertrophy; the nipple-areolar complex is smaller and may lie more superiorly on the affected... Learn more