Tag Archives: peritonitis

What Are the Symptoms of Peritonitis?

Peritonitis is an acute inflammation of the peritoneum triggered by bacterial, chemical or physical insults. It progresses rapidly and may become life-threatening within hours. Key manifestations include:

  1. Abdominal pain
    The earliest and most prominent symptom—persistent, sharp, and diffuse; movement, coughing or palpation intensifies the discomfort.
  2. Peritoneal signs
    Tenderness, rebound pain and guarding give the abdomen a board-like rigidity, reflecting parietal peritoneal irritation.
  3. Nausea & vomiting
    Initially reflex, later bilious or feculent if paralytic ileus supervenes.
  4. Fever & rigors
    Temperature often >38 °C with chills as systemic inflammation ignites.
  5. Abdominal distension
    Gas and fluid accumulate when peristalsis ceases, sometimes compromising respiration.
  6. Cessation of flatus & stool
    Absent bowel sounds confirm adynamic ileus.
  7. Dehydration & thirst
    Fluid loss from vomiting, third-spacing and fever produces dry mucosa and oliguria.
  8. Systemic toxicity & shock
    Endotoxaemia may lead to septic shock: pallor, cold clammy extremities, tachycardia, hypotension, confusion, culminating in multi-organ failure.
  9. Dialysis-fluid changes (in CAPD patients)
    Cloudy effluent with fibrin flecks or strands and catheter-site erythema.

Because fulminant deterioration is common, any patient with sudden severe abdominal pain plus fever, guarding or haemodynamic instability requires immediate evaluation and empiric therapy.

Key AspectTypical Findings
Pain onsetSudden, severe, continuous, worsened by motion
Physical signsTenderness, rebound, board-like rigidity
GI functionNausea, vomiting, absent flatus/stool, silent abdomen
Temperature≥38 °C, often with chills
CirculatoryTachycardia, hypotension → septic shock
RespiratoryShallow breathing due to pain/diaphragmatic splinting
Urinary outputOliguria from hypovolaemia or sepsis
Emergency markerCombination of acute abdomen + fever/shock mandates urgent laparotomy/IV antibiotics

peritoneal thickening

In general, peritoneal thickening is most often caused by abdominal trauma, peritonitis, or metastatic malignancy. Prompt evaluation with contrast-enhanced abdominal CT or PET-CT is essential to establish the exact aetiology; treatment may then include drugs, radiotherapy, chemotherapy, or surgery.

  1. Abdominal trauma
    A direct blow can produce local oedema or haematoma that widens the peritoneal stripe. After imaging to define the extent, small haematomas are managed conservatively, but a full-thickness peritoneal tear requires surgical repair.
  2. Peritonitis
    Bacterial infection, hollow-viscus perforation, or intraperitoneal bleeding can incite marked peritoneal inflammation and subsequent thickening, classically presenting with nausea, vomiting and abdominal pain. Intravenous antibiotics (e.g. ceftriaxone, cefoperazone–sulbactam) are given to control sepsis; laparoscopic lavage or definitive repair is undertaken when indicated.
  3. Malignant peritoneal metastasis
    Advanced gastric, colonic or ovarian cancers may seed the peritoneum, producing plaque-like thickening. Curative resection is seldom possible; cytoreductive surgery is considered only after a good response to systemic chemotherapy or palliative radiotherapy.

Patients should adopt a light, easily digested diet, avoid cold, greasy or irritating foods, and ensure adequate rest and warmth while the diagnostic and therapeutic plan is completed.

CauseMechanism / Key PointsDiagnostic NoteTreatment & Nursing
Abdominal traumaDirect blow → local oedema / haematoma → peritoneal stripe widensCT to size haematoma / detect tearSmall: conservative; Peritoneal tear: surgical repair
PeritonitisBacterial infection, perforation, intraperitoneal bleed → inflammation & thickening; presents with nausea, vomiting, abdominal painCT ± paracentesis; sepsis work-upIV antibiotics (ceftriaxone, cefoperazone-sulbactam); laparoscopic lavage / repair if needed
Malignant metastasisGastric, colonic, ovarian etc. seeds peritoneum → plaque-like thickeningCT + tumour markers; PET-CT for extentSystemic chemotherapy ± palliative RT; cytoreductive surgery only if good response
General supportive careLight, easily digested diet; avoid cold, greasy foods; adequate rest & warmth