Pancreatic endocrine tumors (PETs) are rare neoplasms that arise from the hormone-secreting cells of the pancreas. They can be classified as either functional (hormone-secreting) or non-functional (non-hormone-secreting). The symptoms depend on the type of hormone produced and the size or location of the tumor. Insulin-secreting tumors (Insulinomas) Episodes of hypoglycemia (low blood sugar), especially during fasting or after exercise Symptoms include sweating, palpitations, tremors, confusion, blurred vision, and loss of consciousness Relief of symptoms after glucose intake is typical Gastrin-secreting tumors (Gastrinomas) Recurrent peptic ulcers, often multiple or refractory to treatment Abdominal pain, heartburn, nausea, and vomiting Diarrhea due to... Learn more