Cancer development involves different phases, with tumor spread and metastasis being critical factors that impact treatment and prognosis. These two concepts, though related, have distinct mechanisms and implications. Tumor spread refers to the local infiltration and expansion of cancer cells around the primary site without distant organ involvement. This localized growth can lead to an enlarging primary tumor and invasion of adjacent tissues. Treatment at this stage focuses on controlling the local disease with surgery, radiation, or chemotherapy to prevent further cancer cell infiltration. Metastasis, on the other hand, involves the spread of cancer cells from the primary site to... Learn more

Tumor Lymph Node Metastasis Metastasis to lymph nodes is a significant pathway for cancer spread in the medical field, with various types of tumors exhibiting different propensities for this process. Breast cancer, lung cancer, colorectal cancer, gastric cancer, and head and neck cancers are among the tumor types more likely to metastasize to lymph nodes. Breast cancer often spreads through the lymphatic system, with the axillary lymph nodes being common sites for metastasis. Lung cancer tends to invade the hilar and mediastinal lymph nodes, which is crucial for staging and treatment planning of lung cancer. Involvement of the mesenteric lymph... Learn more