This content is for reference only. For medication use or further health information, please consult a local doctor or pharmacist and take medication appropriately under their guidance.

Main Symptoms of Lower-Limb Lymphedema

Lower-limb lymphedema happens when the lymph system can’t drain fluid from the leg, so the tissue slowly fills up like a wet sponge. It can start after surgery, infection, radiation, or for no clear reason.

Painless swelling is the hallmark. One ankle or calf looks puffy by day and goes down overnight at first, but over time the swelling stays.

Heavy, tight leg follows. Your limb feels like it’s wrapped in wet denim, especially after standing or long flights.

Sock ring stays deep. Elastic leaves a groove that takes minutes to fade, even with loose socks.

Skin changes appear. The leg turns leathery, dry, and may itch or feel tight, like it’s one size too small.

Small blisters or warts pop up. Leaky protein fluid causes tiny bumps that can weep or crust.

Late alarms include repeated skin infections (red, hot, painful), a leg that no longer fits shoes, or fluid leaking through the skin—signs the limb is badly backed up.

SymptomWhat You SeeQuick Check
SwellPuffy ankle/calfOvernight test
HeavyWet-denim feelFlight test
RingDeep sock grooveLoose sock test
SkinLeathery, tightMirror check
BumpsTiny blisters/wartsTouch test
LateRed hot infectionShoe-fit test