Main Clinical Manifestations of Breast Cysts

Breast cysts are fluid-filled, epithelial-lined cavities that develop within terminal ducto-lobular units under hormonal influence. They may be solitary or multiple and are most prevalent in perimenopausal women. Symptom intensity correlates with cyst size, tension, and associated inflammation.

  1. Cyclic or non-cyclic mastalgia
    A well-localised, dull or throbbing pain that increases during the luteal phase; larger cysts produce constant discomfort unrelated to menses.
  2. Palpable, resilient mass
    A smooth, round, mobile lump with distinct borders that may feel fluctuant; tension within the cyst creates a firm “rubber-ball” consistency.
  3. Rapid variation in size
    Cysts may enlarge within days and regress spontaneously, distinguishing them from solid tumours that grow progressively.
  4. Transillumination
    A discrete, well-circumscribed area of light transmission is visible when examined in a darkened room; this sign is lost when cyst wall calcifies.
  5. Nipple discharge
    Clear, serous, or green-brown fluid may be expressed from a single duct; bloody aspirate mandates cytological evaluation to exclude intracystic papilloma or carcinoma.
  6. Tenderness to pressure
    Compression against the chest wall or during mammographic paddles elicits sharp pain; spontaneous relief often follows ultrasound-guided aspiration.
  7. Axillary discomfort
    Reactive, tender lymph nodes < 1 cm are common; firm or matted nodes require biopsy to exclude concurrent malignancy.
  8. Acute inflammatory episode
    Sudden increase in size with erythema and localised heat suggests secondary infection or hemorrhage into the cyst cavity.
Symptom / SignTypical Presentation
MastalgiaCyclic or constant, well-localised
Palpable massSmooth, round, mobile, fluctuant
Size variationRapid enlargement and regression
TransilluminationPositive in tense, thin-walled cysts
DischargeSerous/green; blood → cytology
Pressure tendernessSharp pain, relieved by aspiration
Axillary nodesTender, small; firm nodes need biopsy
InflammationSudden enlargement, erythema, heat