What are the symptoms and manifestations of proctitis?

Proctitis is inflammation limited to the distal 12–15 cm of the rectum. It may be acute or chronic, infectious, inflammatory, ischemic, or radiation-induced. Because the rectum stores stool just before defecation, even limited mucosal irritation produces prominent local symptoms that patients notice immediately.

  1. Core rectal symptoms
  • Tenesmus: a persistent, often painful urge to defecate despite an empty rectum; may interrupt sleep.
  • Urgency: sudden, compelling need to reach a toilet; accidents occur if access is delayed.
  • Frequent, small-volume stools: 5–10 passages daily, each <50 g, sometimes only mucus or blood.
  • Rectal bleeding: bright red streaks on toilet paper, coating stool, or dripping into the pan; clots are rare unless ulcers are deep.
  • Mucus discharge: clear, white, or blood-tinged slime either with stool or spontaneously.
  1. Associated discomfort
  • Burning or aching in the anal canal during and after defecation.
  • Feeling of incomplete evacuation or “blockage” leading to repeated straining.
  • Mild cramping in the suprapubic area; pain rarely localizes to the right or left iliac fossa because the inflamed segment is midline.
  1. Systemic and variant clues
  • Low-grade fever and malaise: suggest bacterial or sexually acquired proctitis.
  • Nocturnal diarrhea: uncommon; if present, consider proximal extension (proctosigmoiditis).
  • Skin or oral lesions: concurrent psoriasis, erythema nodosum, or aphthae point toward inflammatory bowel disease.
  • History of anal-receptive intercourse, recent antibiotic use, or travel: guide microbiologic testing.
  1. Specific context patterns
  • Radiation proctitis: bleeding 6–18 months after pelvic radiotherapy, often with rectal pain and spasm.
  • Ischemic proctitis: sudden bloody diarrhea in older adults with vascular risk factors; pain out of proportion to bleeding.
  • Diversion proctitis: mucus discharge and urgency months after colostomy formation in unused rectal stump.
  1. Red-flag combinations
    Continuous bleeding with orthostatic dizziness, passage of large clots or melena (implying proximal source), severe anal pain suggesting abscess or fistula, and weight loss >5 % within 4 weeks.

Summary table

Key symptomTypical qualityWhen to suspect extension or complications
TenesmusFrequent false urgesPersistence >2 weeks despite topical therapy
Blood on paperBright red, scantClots or melena → colonoscopy
Mucus onlyClear or pinkCopious pus → culture for STI
Urgency<5 min warningAccidents, nocturnal awakening → evaluate proximal spread
Anal painBurning during stoolThrobbing, swelling → rule out abscess