“Stomach disease” is any problem that hurts or upsets the stomach itself. The most common troubles are: Gastritis – redness and swelling of the lining, often from infection, painkillers, alcohol, or stress. Peptic ulcer – a punched-out hole in the lining, usually from the same germ or from daily aspirin or ibuprofen. Stomach cancer – a growth that starts in the lining and can spread. Functional dyspepsia – pain or burning with no clear sore, linked to sensitive nerves or slow emptying. Pyloric stenosis – tight exit door that blocks food from leaving the stomach, seen in babies or after... Learn more