Chronic pancreatitis is a persistent inflammatory-fibrosing condition of the pancreas that destroys exocrine and endocrine tissue. Onset is gradual, with pain dominating early stages and maldigestion or diabetes appearing later. Alcohol, smoking, gene variants, and obstructive causes are common triggers. Symptom recognition allows early enzyme replacement, glycaemic control, and intervention for complications. Pain syndromesEpigastric boring pain: radiates straight through to the back, worse 15–30 min after eating or when lying supine; patients often lean forward or sit on the edge of the bed for relief.Flare-ups: acute-on-chronic episodes with intensified pain, nausea, and tachycardia indistinguishable from acute pancreatitis.Pain-free period: up to... Learn more