Gallstones can lead to weight loss primarily due to the dysfunction of the biliary system, which results in poor digestion and absorption, as well as potential complications. Here’s a detailed explanation of this phenomenon: The presence of gallstones directly impacts the normal secretion and release of bile. Bile is essential for the digestion and absorption of fats; when its secretion is obstructed, fatty foods cannot be effectively broken down and utilized, leading to insufficient nutrient absorption and subsequent weight loss in individuals with gallstones. Gallstones may trigger inflammation in the biliary tract, such as cholecystitis and cholangitis. These inflammatory responses... Learn more