Ependymoma is a brain or spinal-cord tumor that starts in the lining of the fluid-filled spaces inside the skull and spine. Because this lining reaches many areas, symptoms depend on where the tumor is growing and how much it blocks the normal flow of cerebrospinal fluid. The most common early clue is a new headache that is dull and steady, often worse in the morning or when lying flat. Nausea and vomiting may follow the headache, especially if the tumor raises pressure inside the head. Many people feel clumsy or notice weakness in an arm or leg. If the tumor... Learn more