Tag Archives: Breast Fibroadenoma

Main Clinical Manifestations of Breast Fibroadenoma

Breast fibroadenoma is a benign biphasic tumour composed of proliferating glandular and stromal elements. It is the commonest solid breast mass in women under 30 years and is strongly hormone-responsive. Most lesions are solitary and indolent, but multiple or rapidly enlarging variants require exclusion of phyllodes tumour or carcinoma.

  1. Painless, highly mobile nodule
    Typically 1–3 cm, firm, smooth, and well-circumscribed; the “slip sign”—easy displacement under the fingers—distinguishes it from malignant masses that adhere to surrounding tissue.
  2. Smooth, regular margins
    Palpation reveals an ovoid or gently lobulated contour with a distinct edge; deep lesions may feel discoid when compressed against the chest wall.
  3. Hormonal modulation
    Size and tenderness often increase during the luteal phase, pregnancy, or hormone-replacement therapy; spontaneous regression is common after menopause.
  4. Multiple or bilateral occurrence
    Up to 20 % of patients harbour two or more synchronously detectable masses; metachronous contralateral appearance supports a field effect rather than de-novo malignancy.
  5. Giant fibroadenoma (> 5 cm)
    Rapid enlargement can cause visible breast asymmetry, skin venous prominence, and rarely nipple deviation; core biopsy is mandatory to exclude juvenile phyllodes tumour.
  6. Absence of skin or nipple changes
    Erosion, retraction, peau d’orange, or spontaneous discharge are not features of classic fibroadenoma; their presence mandates malignancy work-up.
  7. Stability or slow growth
    Most lesions remain static for months to years; any new irregularity, fixation, or accelerated increase in size warrants imaging-guided core biopsy.
  8. Imaging characteristics
    Ultrasound: hypoechoic, oval mass with gentle posterior enhancement and no internal vascularity on Doppler. Mammography: circumscribed, dense nodule with occasional coarse “pop-corn” calcifications in involuting lesions.
Symptom / SignTypical Presentation
Painless mass1–3 cm, firm, highly mobile, well-circumscribed
Regular marginsSmooth, ovoid or gently lobulated
Hormonal changeEnlarges during luteal phase/pregnancy, regresses post-menopause
Multiple lesions20 % synchronous, bilateral possible
Giant variant> 5 cm, asymmetry, venous pattern, needs biopsy
Skin/nippleNo erosion, retraction, or discharge
Growth patternStable; sudden change → biopsy
ImagingHypoechoic oval on US, circumscribed on MG